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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1970 1
1972 1
1973 1
1974 1
1975 7
1976 6
1977 8
1978 6
1979 12
1980 7
1981 12
1982 15
1983 17
1984 19
1985 29
1986 31
1987 47
1988 40
1989 67
1990 70
1991 91
1992 145
1993 164
1994 208
1995 218
1996 243
1997 225
1998 215
1999 194
2000 215
2001 196
2002 191
2003 199
2004 220
2005 256
2006 241
2007 236
2008 253
2009 235
2010 226
2011 238
2012 305
2013 251
2014 234
2015 232
2016 207
2017 221
2018 200
2019 216
2020 244
2021 220
2022 194
2023 153
2024 58

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6,967 results

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Page 1
Plasma proteomics identifies leukemia inhibitory factor (LIF) as a novel predictive biomarker of immune-checkpoint blockade resistance.
Loriot Y, Marabelle A, Guégan JP, Danlos FX, Besse B, Chaput N, Massard C, Planchard D, Robert C, Even C, Khettab M, Tselikas L, Friboulet L, André F, Nafia I, Le Loarer F, Soria JC, Bessede A, Italiano A. Loriot Y, et al. Ann Oncol. 2021 Nov;32(11):1381-1390. doi: 10.1016/j.annonc.2021.08.1748. Epub 2021 Aug 18. Ann Oncol. 2021. PMID: 34416362 Free article.
RESULTS: By using an unbiased proteomics approach, we show that, in both discovery and validation cohorts, elevated baseline serum level of leukemia inhibitory factor (LIF) is associated with a poor clinical outcome in cancer patients treated with ICB, …
RESULTS: By using an unbiased proteomics approach, we show that, in both discovery and validation cohorts, elevated baseline serum level of …
Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosis.
Xu S, Yang X, Chen Q, Liu Z, Chen Y, Yao X, Xiao A, Tian J, Xie L, Zhou M, Hu Z, Zhu F, Xu X, Hou F, Nie J. Xu S, et al. EBioMedicine. 2022 Dec;86:104312. doi: 10.1016/j.ebiom.2022.104312. Epub 2022 Nov 4. EBioMedicine. 2022. PMID: 36335669 Free PMC article.
However, few studies have ever simultaneously examined them in the same cohort of patients. Besides, the role of leukemia inhibitory factor (LIF) in TIF remains unclear. METHODS: RNA-seq data of kidney biopsies from chronic kidney disease (CKD) patient …
However, few studies have ever simultaneously examined them in the same cohort of patients. Besides, the role of leukemia inhibito …
The dysregulation of leukemia inhibitory factor and its implications for endometriosis pathophysiology.
Zutautas KB, Sisnett DJ, Miller JE, Lingegowda H, Childs T, Bougie O, Lessey BA, Tayade C. Zutautas KB, et al. Front Immunol. 2023 Mar 23;14:1089098. doi: 10.3389/fimmu.2023.1089098. eCollection 2023. Front Immunol. 2023. PMID: 37033980 Free PMC article.
The most common symptoms experienced by patients include manifestations of chronic pelvic pain- such as pain with urination, menstruation, or defecation, and infertility. Alterations to Leukemia Inhibitory Factor (LIF), a cytokine produced by the lumin …
The most common symptoms experienced by patients include manifestations of chronic pelvic pain- such as pain with urination, menstruation, o …
Leukemia inhibitory factor, a double-edged sword with therapeutic implications in human diseases.
Wang J, Chang CY, Yang X, Zhou F, Liu J, Feng Z, Hu W. Wang J, et al. Mol Ther. 2023 Feb 1;31(2):331-343. doi: 10.1016/j.ymthe.2022.12.016. Epub 2022 Dec 26. Mol Ther. 2023. PMID: 36575793 Free PMC article. Review.
Leukemia inhibitory factor (LIF) is a pleiotropic cytokine of the interleukin-6 (IL-6) superfamily. LIF was initially discovered as a factor to induce the differentiation of myeloid leukemia cells and thus inhibit their proliferati …
Leukemia inhibitory factor (LIF) is a pleiotropic cytokine of the interleukin-6 (IL-6) superfamily. LIF w …
Targeting leukemia inhibitory factor in pancreatic adenocarcinoma.
Wang J, Karime C, Majeed U, Starr JS, Borad MJ, Babiker HM. Wang J, et al. Expert Opin Investig Drugs. 2023 May;32(5):387-399. doi: 10.1080/13543784.2023.2206558. Epub 2023 Apr 24. Expert Opin Investig Drugs. 2023. PMID: 37092893 Review.
INTRODUCTION: The Leukemia Inhibitory Factor (LIF) is a member of the interleukin-6 (IL-6) cytokine family. ...LIF has recently emerged as a biomarker and therapeutic target for pancreatic ductal adenocarcinoma (PDAC). ...
INTRODUCTION: The Leukemia Inhibitory Factor (LIF) is a member of the interleukin-6 (IL-6) cytokine family. ... …
Leukemia Inhibitory Factor: An Important Cytokine in Pathologies and Cancer.
Jorgensen MM, de la Puente P. Jorgensen MM, et al. Biomolecules. 2022 Jan 27;12(2):217. doi: 10.3390/biom12020217. Biomolecules. 2022. PMID: 35204717 Free PMC article. Review.
Leukemia Inhibitory Factor (LIF) is a member of the IL-6 cytokine family and is expressed in almost every tissue type within the body. Although LIF was named for its ability to induce differentiation of myeloid leukemia cells, studies of …
Leukemia Inhibitory Factor (LIF) is a member of the IL-6 cytokine family and is expressed in almost every tissue …
Leukemia inhibitory factor (LIF) modulates the development of dendritic cells in a dual manner.
Yaftiyan A, Eskandarian M, Jahangiri AH, Kazemi Sefat NA, Moazzeni SM. Yaftiyan A, et al. Immunopharmacol Immunotoxicol. 2019 Jun;41(3):455-462. doi: 10.1080/08923973.2019.1619761. Epub 2019 May 30. Immunopharmacol Immunotoxicol. 2019. PMID: 31142168
Objective: Dendritic cells (DCs) are professional antigen presenting cells majorly modulated by various environmental factors. Leukemia inhibitory factor (LIF) is a pleiotropic cytokine from interleukin-6 family. ...Materials and methods: To clarify th …
Objective: Dendritic cells (DCs) are professional antigen presenting cells majorly modulated by various environmental factors. Leukemia …
The emerging role of leukemia inhibitory factor in cancer and therapy.
Zhang C, Liu J, Wang J, Hu W, Feng Z. Zhang C, et al. Pharmacol Ther. 2021 May;221:107754. doi: 10.1016/j.pharmthera.2020.107754. Epub 2020 Nov 28. Pharmacol Ther. 2021. PMID: 33259884 Free PMC article. Review.
Leukemia inhibitory factor (LIF) is a multi-functional cytokine of the interleukin-6 (IL-6) superfamily. ...Emerging evidence has shown that LIF plays an important but complex role in human cancers; while LIF displays a tumor suppressive …
Leukemia inhibitory factor (LIF) is a multi-functional cytokine of the interleukin-6 (IL-6) superfamily. ...Emer …
Leukemia inhibitory factor suppresses hepatic de novo lipogenesis and induces cachexia in mice.
Yang X, Wang J, Chang CY, Zhou F, Liu J, Xu H, Ibrahim M, Gomez M, Guo GL, Liu H, Zong WX, Wondisford FE, Su X, White E, Feng Z, Hu W. Yang X, et al. Nat Commun. 2024 Jan 20;15(1):627. doi: 10.1038/s41467-024-44924-w. Nat Commun. 2024. PMID: 38245529 Free PMC article.
Cancer cachexia is a systemic metabolic syndrome characterized by involuntary weight loss, and muscle and adipose tissue wasting. Mechanisms underlying cachexia remain poorly understood. Leukemia inhibitory factor (LIF), a multi-functional cytokine, ha …
Cancer cachexia is a systemic metabolic syndrome characterized by involuntary weight loss, and muscle and adipose tissue wasting. Mechanisms …
Leukemia inhibitory factor (LIF) potentiates antinociception activity and inhibits tolerance induction of opioids.
Tu HJ, Kang KH, Ho SY, Liou HC, Liou HH, Lin CP, Fu WM. Tu HJ, et al. Br J Anaesth. 2016 Oct;117(4):512-520. doi: 10.1093/bja/aew247. Epub 2016 Oct 17. Br J Anaesth. 2016. PMID: 28077540 Free article.
Glial activation and the upregulation of proinflammatory cytokines are related to the induction of tolerance. We investigated the effect of leukemia inhibitory factor (LIF) on morphine analgesia and tolerance. ...The development of tolerance was marked …
Glial activation and the upregulation of proinflammatory cytokines are related to the induction of tolerance. We investigated the effect of …
6,967 results